(June 26, 2012) -- The last time Kip Wells stepped on the mound was in 2009 with the Cincinnati Reds. In 2012, Wells completed his comeback story to the majors with the San Diego Padres.

But the return was not a pleasant one. A four-run fifth inning, capped with a J.D. Martinez two-run homer, as well as a Jed Lowrie solo shot, handed the starter a 5-3 loss against the Houston Astros Tuesday night.

Houston starter Jordan Lyles (2-4) allowed six hits and a run in 6 1-3 innings to break a three-game losing streak and earn his first victory since June 3.

The game was tied at 1 after Will Venable and Lowrie exchanged solo homers in the third.

Houston took the lead when a run scored on a wild pitch and extended it with an RBI single by Chris Johnson. Martinez's soaring drive to left-center off starter Kip Wells (0-1) made it 5-1.